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CKD-EPI Estimated Glomerular Filtration Rate (eGFR

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Estimated Glomerular Filtration Rate (eGFR) is the premier clinical index of kidney function.

Reviewed by Dr. Shahzad · DHMS, RMP
Last updated:
Editorial Guidelines

⚙ Input Values

mg/dL
years

📊 Results

Estimated GFR (eGFR)
59.3
mL/min/1.73m²
Chronic Kidney Disease (CKD) Stage
CKD Stage 3a (eGFR 45 - 59): Mild to moderate reduction.
National Kidney Foundation Interpretation
Moderate kidney function decline; consult physician.
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📐 Formula

2021 CKD-EPI Race-Free Equation:
eGFR = 142 × Min(Scr/κ, 1)^α × Max(Scr/κ, 1)^-1.200 × 0.9938^Age × (1.012 if Female)
Where κ = 0.7 (female) or 0.9 (male), α = -0.241 (female) or -0.302 (male)

💡 Practical Example

✅

55-year-old female with serum creatinine Scr = 1.10 mg/dL: eGFR = 142 ×^-1.200 × 0.9938^55 × 1.012 = 62.4 mL/min/1.73m² (CKD Stage 2 Mild Reduction).

📖 About CKD-EPI Estimated Glomerular Filtration Rate (eGFR

Estimated Glomerular Filtration Rate (eGFR) is the premier clinical index of kidney function. The 2021 CKD-EPI equation calculates eGFR without race variables according to National Kidney Foundation (NKF) guidelines.

To use the CKD-EPI Estimated Glomerular Filtration Rate (eGFR) Calculator, enter your Serum Creatinine (Scr), Patient Age, Biological Gender. The calculator instantly computes Estimated GFR (eGFR), Chronic Kidney Disease (CKD) Stage and more. Results update in real time as you change any input — no submit button needed.

How to Use This Calculator

Enter your Serum Creatinine (Scr) (e.g. 1.10 in mg/dL), Patient Age (e.g. 55 in years), and Biological Gender — select from Female, Male. Results update instantly — no submit button needed. Use metric or imperial units as labeled. For the most accurate result, measure height and weight in the morning without shoes.

The Formula

2021 CKD-EPI Race-Free Equation:

eGFR = 142 × Min(Scr/κ, 1)^α × Max(Scr/κ, 1)^-1.200 × 0.9938^Age × (1.012 if Female)

Where κ = 0.7 (female) or 0.9 (male), α = -0.241 (female) or -0.302 (male)

Worked Example

55-year-old female with serum creatinine Scr = 1.10 mg/dL:

eGFR = 142 ×^-1.200 × 0.9938^55 × 1.012 = 62.4 mL/min/1.73m² (CKD Stage 2 Mild Reduction).

Understanding Your Result

KDIGO (Kidney Disease: Improving Global Outcomes) eGFR staging: G1 Normal ≥90 mL/min/1.73m². G2 Mildly decreased 60–

  • G3a Mild-moderately decreased 45–
  • G3b Moderately-severely decreased 30–
  • G4 Severely decreased 15–
  • G5 Kidney failure below
  • eGFR naturally declines approximately 1 mL/min/1.73m² per year after age 40 — a single reading must be interpreted in context of age, hydration status, and trend over time. Two readings more than 3 months apart are needed to confirm CKD staging.

💡 Expert Health Guidance & Clinical Context

  • This calculator uses clinically validated formulas and population reference data published by the WHO and NIH. Results are screening estimates, not medical diagnoses.
  • Consult a licensed healthcare provider before making any changes to diet, medication, or exercise based on these results — individual variation is significant.
  • Genetics, chronic conditions, and concurrent medications can dramatically affect what a "normal" result means for a specific individual.
  • Track your results over time: a single data point is less meaningful than a trend measured consistently across multiple weeks or months.
  • The CDC recommends adults receive routine health screenings at least annually. Use these calculations to prepare informed questions for your physician.
  • Body composition, lifestyle factors, and stress levels all interact with the metrics shown here. No single number captures your full health picture.
  • For pediatric or geriatric populations, reference ranges may differ significantly from the adult standards used in general calculators.
  • Always cross-reference results with laboratory tests, clinical examinations, and professional medical evaluation before acting on any finding.

Results are for informational and educational purposes only. Always verify critical decisions with a qualified professional.

❓ Frequently Asked Questions

What is a normal eGFR level?

An eGFR of 90 mL/min/1.73m² or higher is considered normal. An eGFR below 60 for 3+ months indicates Chronic Kidney Disease.

What is the 2021 CKD-EPI equation?

The 2021 CKD-EPI equation is the updated ANSI/NKF race-free standard for estimating GFR using serum creatinine, age, and biological sex.

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